De Soto Senior High School
| Full Name: | De Soto Senior High School |
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| Short Name: | De Soto |
| Type: | High School (Public) |
| Team Nickname: | Dragons |
| Website: | https://shs.desoto.k12.mo.us/ |
| Address: | 815 Amvets Drive De Soto, MO 63020 |
| Phone: | 636-586-1085 |
| Fax: | 636-586-1059 |
| Program Status: | Active |
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Coach
Jennifer Kidwell